WebJan 1, 2024 · Chlamydia trachomatis is part of the chlamydophila genus. These bacteria are gram-negative, anaerobic, intracellular obligates that replicate within eukaryotic cells. C. trachomatis differentiates into 18 serovars (serologically variant strains) based on monoclonal antibody-based typing assays. WebC. trachomatis STIs are best identified in genital samples using nucleic acid amplification tests (NAATs) because these tests are more sensitive than cell culture and have less stringent sample handling requirements. Currently, 6 NAATs are approved by the U.S. Food and Drug Administration (FDA) for testing genital and urine specimens from adults and …
Diagnostic Procedures to Detect Chlamydia trachomatis Infections
WebThis property makes Chlamydia difficult organisms to grow and maintain in the laboratory. Up until 1965, passage in the yolk sac of the embryonated hen egg was the only way to … WebJan 11, 2024 · Chlamydia trachomatis is an obligate intracellular bacterium that grows within a mammalian host cell for survival. The bacteria cannot be cultured via conventional cultural methods on bacteriological medium. This also makes C. trachomatis a difficult organism to grow and maintain in most laboratories. poorly distended
Chlamydia Article - StatPearls
WebAcceptable Specimens. Specimen Handling Collection Transport Reporting. Culture swabs and tissues must be kept moist in Viral or Chlamydia Transport Media, M4 or M5. Specimens must not be leaking. Body fluids and wash specimens for viral culture should be transported in sterile containers, without dilution in transport media. WebCulture should be the test-of-choice in cases of child abuse, rectal and throat infections, and when a test for cure is desired. Chlamydia is a single genus and consists of the … WebAug 5, 2016 · The intracellular life style of chlamydia and the ability to cause persistent infections with low-grade replication requires tests with high analytical sensitivity to directly detect C. trachomatis (CT) in medical samples. Nucleic acid amplification tests (NAATs) are the most sensitive assays with a specificity similar to cell culture and are considered … poorly differentiated neuroblastoma